Radiofrequency ablation of genicular nerve versus intra-articular botox injection for knee osteoarthritis pain

Radiofrequency ablation of genicular nerve versus intra-articular botox injection for knee osteoarthritis pain; a randomized single blinded study.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202301832676408

Enrollment

Registered

2023-01-25

Start date

2022-09-07

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

analgesia for chronic osteoarthritis.

Interventions

Radiofrequency ablation of genicular nerves.

knee intraarticular Botox injection

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: • Patients with chronic primary knee osteoarthritis. • Age > 40 years. • Failure to respond to other non-interventional therapies (physical therapy and rehabilitation, oral NSAIDs). • Grade III – IV according to the Kellgren-Lawrence Grading Scale on a documented radiological study.

Exclusion criteria

Exclusion criteria: • Secondary osteoarthritis. • Body mass index (BMI) > 35 kg/m2. • Ongoing psychiatric illness. • Presence of infections at the injection site. • Malignancy. • Coagulopathy or use of anticoagulants. • History of rheumatological disorders, prolotherapy, or intraarticular injection in the three months. • History of trauma within 3 months before the study. • Presence of an indication for arthroplasty.

Design outcomes

Primary

Measure	Time frame
•Improvement in pain (VAS) for 6 months after therapy	—

Secondary

Measure	Time frame
The patient will be followed up for 6 months after procedure • Procedural complications. • Patient satisfaction	—

Countries

Egypt

Contacts

Public ContactIbrahim;Khalid Abdelbaser;elbahrawy

Assistant professor;assistant professor

ibrahimbaser2010@yahoo.com;Khali_bahrawy@gmail.com01004976825;00201067240357

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026