Role of early mitomycin application in pediatric corrosive ingestion

Early endoscopic mitomycin application in pediatric esophageal corrosive ingestion

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

PACTR

Registry ID

PACTR202301748506567

Enrollment

Registered

2023-01-31

Start date

2020-12-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Digestive System Injury, Occupational Diseases, Poisoning Paediatrics

Interventions

Topical application of mitomycin over esophageal mucosa

Upper endoscopy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Any child age up to 18 yr Corrosive esophagitis grade 3 In early 48 hours from corrosive ingestion

Exclusion criteria

Exclusion criteria: Unstable hemodynamic and respiratory system Impending perforation After 48 hours from corrosive ingestion

Design outcomes

Primary

Measure	Time frame
Assess the efficacy of topical application of mitomycin over esophageal mucosa in pediatric corrosive ingestion patient in decrease the incidences of subsequent esophageal stricture	—

Secondary

Measure	Time frame
Compare the cost effectiveness between mitomycin application and conventional endoscopic procedure	—

Countries

Egypt

Contacts

Public ContactSara Tarek

Lecturer in pediatric Cairo university Egypt

sara.tarek2310@outlook.com01205551917

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026