Tuberculosis
Conditions
Interventions
Video instruction for sputum production
Sponsors
Research Institute of Tuberculosis RIT
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: • Symptoms suggestive of pulmonary TB and/or an abnormal chest X-ray • Able and willing to provide written informed consent (>20 years) or minor assent (12-20) and parental consent for participants 6-20 years. • Able to understand instructions in one of the four commonly used languages (English, French, Fulfulde, Pidgin)
Exclusion criteria
Exclusion criteria: • Contraindicated for sputum induction (Asthma, with acute exacerbation in last two weeks (any attack within the last two weeks); dyspnea or respiratory distress, grade 3 or 4, in the last one week; hypoxemia (SpO2 <90% in ambient air); hemoptysis (coughing up blood), in last one week; history of esophageal operation; known eardrum damage or other middle ear lesions; acute sinusitis, with documentation; nosebleed, in the last one week; nausea, grade 3 or 4, in the last two days; vomiting, grade 3 or 4, in the last two days) • Currently on TB treatment • Inability to sit upright for 20 minutes • Refusal to signed informed consent form or assent form (12-20 years) or parental informed consent form (6-20years). • Other issue raised for exclusion based on the judgement of the clinical and/or study personnel
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The estimated proportion of people testing positive for TB | — |
Secondary
| Measure | Time frame |
|---|---|
| Sputum quantity (1-2mL, >2-3mL, >3-4mL, >4mL) ;Adverse events or symptom aggravation, with severity grading;Cost per participant tested Cost per TB case diagnosed ;Incremental cost per TB case diagnosed/per participant tested | — |
Countries
Cameroon
Contacts
Public ContactSatoshi Mitarai
Research Institute of Tuberculosis
Outcome results
None listed