Diclofenac versus Pentazocine Hydrocloride for analgesia In first stage labour: a Randomised Controlled Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202212654526624

Enrollment

650

Registered

2022-12-21

Start date

2019-12-11

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth

Interventions

PENTAZOCINE HYDROCLORIDE group

DICLOFENAC group

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Previously selected booked primigravidae and multiparous women (Para 1–4) with a term pregnancy admitted to the labour room in the active phase of labour with a cervical dilatation from 4–7cm with no contraindication to the use of diclofenac or pentazocine. 2. Women in active phase labour with singleton fetus.

Exclusion criteria

Exclusion criteria: 1. Unbooked status. 2. History of medical diseases (diabetes mellitus, hypertension, cardiac deceases, chronic renal disease, peptic ulcer disease, bleeding disorder and bronchial asthma). 3. Grandmultiparity 4. History of previous uterine scar, multiple gestation, preterm labour 5. History of opioid addiction

Design outcomes

Primary

Measure	Time frame
1. Pain score recorded at 30, 60 and 120 minutes following injection of IM diclofenac 75mg. 2. Pain score recorded at 30, 60 and 120 minutes following injection of IM pentazocine 30mg.	—

Secondary

Measure	Time frame
1. Maternal side effects of diclofenac noted 2. Fetal side effects of diclofenac noted 4. Maternal side effects of pentazocine noted 5. Fetal side effects of pentazocine noted	—

Countries

Nigeria

Contacts

Public ContactIkechukwu Dimejesi

consultant

ikedimejesi@gmail.com08033656433

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026