Anterior Lumbar Interbody Fusion versus Posterior Transforaminal Lumbar Interbody Fusion for treatment of Lumbar Degenerative Diseases.

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

PACTR

Registry ID

PACTR202211721074384

Enrollment

100

Registered

2022-11-30

Start date

2022-10-25

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery

Interventions

Anterior lumbar fusion ALIF OLIF

Posterior TLIF

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All cases operated upon for degenerative lumbar spinal disorders by anterior lumbar fusion either ALIF or ATP during 2015 to 2023, in addition to, a group of TLIF cases matched the same criteria ( diagnosis, level, number of levels, age group,…) treated within the same period. All approaches are used for management of degenerative spinal diseases according to the surgical experience and preference

Exclusion criteria

Exclusion criteria: - Previous abdominal surgery with severe adhesion. - Non degenerative spinal pathology or severe osteoporosis or severe peripheral vascular disease - Patient with incomplete files or in complete follow up

Design outcomes

Primary

Measure	Time frame
Lumbar fusion rate. Bridwell interbody fusion grading system is the basis for the fusion rate-grading criterion. Grades I and II as successful grades	—

Secondary

Measure	Time frame
• Radiological evaluation: including ADH, PDH, SLA, and FH before the surgery and at the last follow up along with cage position only at the post-operative serial follow up X. rays. • Surgical procedures and complications including operative time, blood loss, number of surgeries. Complications, intraoperative complication (anaesthesia, dural tear, neurological lesion, vascular injury or visceral injury), Postoperative complications: superficial infection, deep infection, neurological lesion, vascular lesion, hematoma, ipsilateral psoas paresis, ipsilateral quadriceps weakness, left lower abdominal pain, incomplete ileus, sympathetic chain symptom, metal malposition and cage shifting. Adverse effects: death, deep venous thrombosis, pulmonary embolism, pneumonia, urinary infection, acute respiratory insufficiency, multiple organ failure, sepsis, implant breakage or loosening, and need for reoperation.	—

Measure

Time frame

• Radiological evaluation: including ADH, PDH, SLA, and FH before the surgery and at the last follow up along with cage position only at the post-operative serial follow up X. rays. • Surgical procedures and complications including operative time, blood loss, number of surgeries. Complications, intraoperative complication (anaesthesia, dural tear, neurological lesion, vascular injury or visceral injury), Postoperative complications: superficial infection, deep infection, neurological lesion, vascular lesion, hematoma, ipsilateral psoas paresis, ipsilateral quadriceps weakness, left lower abdominal pain, incomplete ileus, sympathetic chain symptom, metal malposition and cage shifting. Adverse effects: death, deep venous thrombosis, pulmonary embolism, pneumonia, urinary infection, acute respiratory insufficiency, multiple organ failure, sepsis, implant breakage or loosening, and need for reoperation.

—

Countries

Egypt

Contacts

Public ContactYousef Saleh

Vice Dean for Graduate Studies and Research

youssef66@aun.edu.eg+20882413232

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026