Surgery Anaesthesia
Conditions
Interventions
Group A
Group B
Group C
Sponsors
Dr Naa Martekuor Vanderpuye
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients above 18 years requiring endotracheal intubation 2. Patients with BMI <30 3. Patients with ASA classification I or II All elective general surgery patients requiring endotracheal intubation who meet above inclusion criteria and give a signed or thumb-printed informed consent to participate in this study will be included except:
Exclusion criteria
Exclusion criteria: • Patients 18years of age who are mentally incapacitated. • Patients with ASA III and IV, as these may be too sick with uncontrolled co-morbidities. • Patients who have an Upper Respiratory Tract Infection prior to surgery (sore throat, cough, running nose), as these may make assessment of tracheal morbidities difficult. • Patients coming for head and neck surgeries as manipulations during these surgeries could in themselves cause laryngeal morbidity. • Patients who will have their surgical cases done in the prone position. • Patients with a history of Asthma. These patients have a reactive airway and are prone to airway complications during intubation. • Patients with a history of difficult intubations, anticipated difficult intubation, and those who will have multiple attempts at intubation. • Patients with known anatomical laryngo-tracheal abnormalities, snoring and gastroesophageal reflux. • Patients who will require post-operative intubation and so cannot have the occurrence of tracheal morbidity 24 hours post-operatively assessed. • Patients who are obese (BMI >35kg/m2) ( they are high risk for difficult intubation and ventilation as well as develop airway complications more easily)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected that the subjects in the groups who had their ETT cuffs inflated with Magnesium Sulphate, or received intravenous Magnesium Sulphate, will have a reduction in the occurrence of post extubation sore throat, cough and hoarseness. | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate and Blood pressures will be better controlled in the groups where the patients were given intravenous magnesium or intracuff magnesium | — |
Countries
Ghana
Contacts
Public ContactEbenezer Owusu Darkwa
Supervisor
Outcome results
None listed