Skip to content

CHLORHEXIDINE MOUTHWASH TO REDUCE RESPIRTAORY TRACT INFECTIONS AFTER ABDOMINAL SURGERIES

RANDOMIZED PLACEBO-CONTROLLED TRIAL TESTING 0.2% CHLORHEXIDINE MOUTHWASH TO REDUCE POSTOPERATIVE RESPIRATORY TRACT INFECTIONS IN ABDOMINAL SURGERIES

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
PACTR
Registry ID
PACTR202211513812190
Enrollment
104
Registered
2022-11-28
Start date
2022-12-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory

Interventions

chlorhexine gluconate mouthwash
distilled water

Sponsors

TAMALE TEACHING HOSPITAL
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Participants who are 10 years and above 2. Participants presenting with either elective or emergency abdominal condition requiring midline laparotomy under general anaesthesia 3. Midline incision of at least 5cm long or more 4. Participants who have given written informed consent and/or assent

Exclusion criteria

Exclusion criteria: 1. Non-midline abdominal incision 2. Emergency laparotomy for gynaecological conditions including caesarean sections 3. Patients who have documented allergy or hypersensitivity to chlorhexidine 4. Patients with documented evidence of pneumonia before surgery 5. Incisions less than 5cm 6. Those unable to complete follow up after surgery 7. Patients assessed to have ASA grade V, expected to die with or without surgery, before the commencement of surgery 8. Patients who have had abdominal surgery in another facility and referred to TTH for further management

Design outcomes

Primary

MeasureTime frame
respiratory tract infection

Secondary

MeasureTime frame
mortality;length of hospital stay;return to normal activity;unplanned readmission due to a respiratory complication

Countries

Ghana

Contacts

Public ContactSHAMUDEEN MOHAMMED ALHASSAN

DEPUTY DIRECTOR AND HEAD OF RESEARCH AND DEVELOPMENT TTH

mohammed.shamudeen-alhassan@tth.gov.gh+233372000180

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026