Eye Diseases Anaesthesia
Conditions
Sponsors
Pr. Hosni KHOUADJA
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: oral and written informed consent of the patients an age over 50 years old an ASA class I, II, III a cataract of senile origin a cataract complicating an ophthalmological pathology such as uveitis or pigmentary retinopathy a cataract complicating an extra-orbital pathology such as diabetes, chronic inflammatory diseases and hypoparathyroidism a post-traumatic cataract a cataract of iatrogenic origin following long-term corticosteroid therapy or orbital radiation therapy
Exclusion criteria
Exclusion criteria: a psychiatric history a history of long-term use of sedatives, anxiolytics or analgesics a history of complications from ophthalmic surgery sleep disorders cognitive or sensory disorders a congenital cataract (embryopathies or hereditary) a cataract secondary to genetic diseases such as Trisomy 21 or Steinert’s dystrophy a secondary cataract on implant following a posterior capsular opacification a strong myopia staphyloma a glaucoma in the controlateral eye a contraindication of the use of melatonin a contraindication to loco-regional anesthesia any indications to convert to general anesthesia such as failure of loco-regional anesthesia technique failure to comply with the 60-minute premedication period a surgical procedure that has exceeded the half-elimination time of melatonin (120 minutes) an intra operative anesthetic complications an intra operative surgical complications such as an expulsive hemorrhage of the eyeball, rupture of the capsule with vitreous exit, capsular or zonular rupture, or a non compliant implant
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| a 50 percent reduction in the average total dose of intraoperative midazolam and alfentanyl consumption with melatonin premedication | — |
Secondary
| Measure | Time frame |
|---|---|
| intra operative sedation ;intraoperative analgesia;Perioperative anxiety;Intraocular pressure;Patients satisfaction;Surgeons satisfaction;total dose of bolus of nicardipine ;recovery of psychomotor function;advese effects of melatonin;heart rate;respiratory rate;Pulsed O2 saturation;Systolic arterial blood pressure;Diastolic arterial blood pressure;Mean arterial blood pressure;Occurence of an oculo-cardiac reflex | — |
Countries
Tunisia
Contacts
Public ContactFadoua MIGHRI
Anesthesia and intensive care department
Outcome results
None listed