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Dexmedetomidine (10 µg) versus Fentanyl (25 µg) as adjuvants to hyperbaric Bupivacaine for unilateral spinal anesthesia in lower limb orthopedic surgeries

Dexmedetomidine (10 µg) versus Fentanyl (25 µg) as adjuvants to hyperbaric Bupivacaine for unilateral spinal anesthesia in lower limb orthopedic surgeries

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202209726231234
Enrollment
54
Registered
2022-09-05
Start date
2022-05-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

dexmedetomidine
fentanyl

Sponsors

faculty of medicine Ain Shams University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: -Age =21 years and <65 years. -ASA grade I and II -both sexes -Patients undergoing elective orthopedic surgeries of lower limb.

Exclusion criteria

Exclusion criteria: -Any patient who has history of heart failure (NYHA class ?,?), neuropathy , uncontrolled hypertension, drug abuse, or allergy to the study drugs or has any contraindication of spinal anesthesia -Patients who can't be placed in a lateral position (e.g., due to pelvis fracture)

Design outcomes

Primary

MeasureTime frame
is to measure the time taken for the patient to rescue analgesia

Secondary

MeasureTime frame
is to measure : • Time from injection to highest sensory level • Time to two segment regression from the highest sensory level • Time for sensory regression to S1 from highest sensory level • Time from injection to Bromage ? • Time to regression to Bromage 0 • Side effects like nausea, vomiting, shivering or respiratory depression for 4 hours after performing spinal anesthesia • Sedation level will be assessed using modified Ramsay scale

Countries

Egypt

Contacts

Public Contactmariam gamal

assisstant lecturer

gmariam488@gmail.com00201273393347

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026