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Prospective study evaluating the efficacy of ventricular irrigation in the treatment of the bacterial ventriculitis (VIP STUDY)

Prospective study evaluating the efficacy of ventricular irrigation in the treatment of the bacterial ventriculitis (VIP STUDY)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202209722364968
Enrollment
240
Registered
2022-09-21
Start date
2022-10-03
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bacterial Ventriculitis Nervous System Diseases Surgery Paediatrics

Interventions

Parenteral Antibiotics standard of care
Ventricular Irrigation and Parenteral Antibiotics VT group

Sponsors

Cure Childrens Hospital of Uganda
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All patients zero to twelve month of age admitted with a diagnosis of bacterial ventriculitis will be included 1. Age 0 days to 12 months 2. Any patient with clinical and laboratory evidence of bacterial ventriculitis

Exclusion criteria

Exclusion criteria: 1. Any eligible patient whose caregiver declines participation in the study. 2. Any patient that does not meet the inclusion criteria listed above. 3. Any patient with ventriculitis not attributed to a bacterial cause. 4. Any eligible patient from distant locations especially out of Uganda.

Design outcomes

Primary

MeasureTime frame
Time to sterilization of CSF. This will be determined as the time in days taken from intervention to sterilization of CSF

Secondary

MeasureTime frame
Time in days to definitive Surgical Intervention ;All cause mortality rates between study arms at 30 days post intervention;Neurological outcome between the study arms; ;Radiological evidence of disease progression after intervention

Countries

Uganda

Contacts

Public ContactBetty Nantongo

Anaesthesiologist

nantongo109@gmail.com+256776415246

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026