Musculoskeletal Diseases
Conditions
Interventions
Pain Neuroscience Education
Control
Sponsors
Tyren Naidoo
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion Criteria • Signed informed consent. • Participants aged 18 to 65 years (Knechtle and Nikolaidis 2018; Larsen et al. 2020). • Participants who are male or female with symptomatic chronic knee pain (greater than 3 months duration). • Participants with a weekly training volume between 30 and 80km/week (Rasmussen et al. 2013). • Participants who had completed 2 or more marathon events within the past 2 years (virtual and non-virtual). • Participants with a score greater than 40 on the central sensitization inventory scale (CSI) (Mayer et al. 2012).
Exclusion criteria
Exclusion criteria: Exclusion Criteria • Professional and elite marathon runners (Rüst et al. 2011). • Participants who have had previous total knee replacement or any other lower limb surgery within the past six months of the affected knee, co-existing inflammatory, metabolic or neurologic disease (Messier et al. 2008; Lluch et al. 2018). • Participants who have contraindications to chiropractic care and PNE. • Participants who have previously received chiropractic care and/or PNE can require a 3 month wash out period before they can be eligible to enter the study. • Participation in other pain trials prior (3 months) to recruitment. • Lack of the ability to adhere to the protocol, cognitive impairment, illiteracy or unable to speak English (Lluch et al. 2018).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measure the difference between manipulation and Pain neuroscience education combined | — |
Secondary
| Measure | Time frame |
|---|---|
| Measure the difference with manipulation alone. | — |
Countries
South Africa
Contacts
Public ContactLinda Twiggs
Clinic Administrator
Outcome results
None listed