Fertility-female
Conditions
Interventions
drug
Sponsors
Ain Shams University Maternity Hospital and Adam International Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: o Female age between 18 and 40 years. o Primary or secondary infertility. o Baseline FSH and LH lower than 12 IU/l. o Body mass index (BMI) between 18 and 40kg/m2.
Exclusion criteria
Exclusion criteria: o Ovarian endometriosis. o Ovarian cysts before induction. o Known endocrinal abnormalities (like hypo or hyperthyroidism, hyperprolactinemia, pituitaryabnormalities). o AMH = 10 ng/ml. o Duration of induction 6 days or less. or Duration of induction more than 16 days. o E2 drop during induction. o Last E2 level before trigger more than 10000pg/ml. o Immature oocytes syndrome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ovarian hyperstimulation syndrome OHSS rate | — |
Secondary
| Measure | Time frame |
|---|---|
| 1-Oocyte maturation rate Percentage of Mature oocytes (MII) retrieved. 2-Fertilization rate Fertilization rate (FR) is percentage of transformation of micro injected oocytes into two pronuclei 3-Blastulation rate Blastulation rate is defined as the total number of blastocysts in a cycle (including those transferred and cryopreserved) divided by the total number of fertilized oocytes (Jones et al., 2020). 4-Biochemical pregnancy rate Biochemical pregnancy is a pregnancy diagnosed only by the detection of beta hCG in serum or urine 5-Clinical pregnancy rate Clinical pregnancy rate is the number of clinical pregnancies expressed per 100 initiated cycles, aspiration cycles or embryo transfer cycles. When clinical pregnancy rates are recorded, the denominator (initiated, aspirated orembryo transfer cycles) must be specified 6-Miscarriage rate Miscarriage is generally defined as a nonviable intrauterine pregnancy up to 20 weeks gestation | — |
Countries
Egypt
Contacts
Public ContactMarwa Snosi
Lecturer of obstetrics and gynecology Ain Shams University
Outcome results
None listed