Pregnancy and Childbirth
Conditions
Interventions
control group
study group
Sponsors
faculty of medicine suez canal university
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1) Age from 18- 45 years. 2) Patients are ASA I (American Society of Anesthesiology physical status Grade I) = (normal healthy patients) or ASA II (American Society of Anesthesiologists physical status Grade II) = (patients with mild systemic disease and no functional limitations). 3) term with singleton uncomplicated pregnancies. 4) Body mass index of at most 40 kg/m2.
Exclusion criteria
Exclusion criteria: 1) Parturient with peri-partum disorders as DM, HTN, cardiac diseases, Sickle cell disease or bleeding disorders History of venous (deep vein thrombosis and/or pulmonary embolism) or arterial (angina pectoris, myocardial infarction, stroke) thrombosis. 2) Known case of coagulation disorders. 3) Severe anemia. 4) Allergy to TXA. 5) Severe medical and surgical complications involving the heart, liver, kidney, brain, and blood disorder. 6) Abnormal placenta such as placenta previa and placental abruption. 7) Pregnancy related complication like severe preeclampsia, 8) Pregnancy with <37 weeks gestational age. 9) Woman on anticoagulant therapy during the week 10) Refusal to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Amount pf perioperative blood loss as mentioned before 2.Change in hemoglobin level in gm measured after 48 hrs | — |
Secondary
| Measure | Time frame |
|---|---|
| 3. Need for vasopressors to maintain blood pressure within accepted level 4. Incidence of severe PPH, defined by blood loss =1000 mL. 5. Incidence of nausea, vomiting and thrombosis | — |
Countries
Egypt
Contacts
Public Contactomima taha
assistant professor suez canal university
Outcome results
None listed