Circulatory System Surgery Anaesthesia
Conditions
Interventions
Group 1
group 2
Group 3
Sponsors
Dilla University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: - ASA I and II - age 18-65 yrs
Exclusion criteria
Exclusion criteria: - patients with a history of PONV, motion sickness, gastroparesis, bradycardia, atrioventricular block, and severe cardiac dysfunction, diabetes, hypertension, coronary heart disease, liver, and kidney function seriously damaged, chronic pain, chronic opioid users, upper respiratory tract infection, asthma, smoking
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Our primary endpoints will be to investigate the effect of different doses of dexmedetomidine infusion on hemodynamic response to critical incidences such as laryngoscopy, endotracheal intubation, surgical incision, and extubation in patients undergoing open abdominal surgery. A change in hemodynamic parameters (MAP, SBP, and HR) from baseline will be compared to the subsequent repeated measurements. | — |
Secondary
| Measure | Time frame |
|---|---|
| Our secondary endpoints are to observe the effects on extubation time, post-operative sedation levels in the PACU, postoperative nausea and vomiting, postoperative pain score and analgesic requirements, time to first analgesic request, and occurrence of adverse effects. Postoperative analgesia therapy will be provided when patients complain of pain (request medication) or a numeric rating scale=of 4 is recorded. The analgesic drugs administered will be as per the hospital protocol. | — |
Countries
Ethiopia
Contacts
Public ContactTeshome Regasa
Public Enquries
Outcome results
None listed