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Effect of Branched-Chain Amino Acids Supplementation on Physical and Cognitive Performance and Biological Responses

Effect of Branched-Chain Amino Acids Supplementation on Physical and Cognitive Performance and Biological Responses

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
PACTR
Registry ID
PACTR202208691866055
Enrollment
10
Registered
2022-08-19
Start date
2023-01-02
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nutritional, Metabolic, Endocrine

Interventions

Placebo control
Low dose of BCAA
High dose of BCAA
Pre Test BCAA Supplementation
Post Test BCAA Supplementation
Leucine Enriched BCAA 1
Leucine Enriched BCAA 2

Sponsors

Laboratory of Biochemistry CHU Habib Bourguiba
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: Participants trained at least 4 sessions per week with at least 3 years of training history. aged at least 19 years old. Injury-free.

Exclusion criteria

Exclusion criteria: exhibited dysfunctional symptoms of the musculoskeletal or cardio-pulmonary system. Consuming creatine within the past six months and taking any antioxidant (e.g., vitamin E, A, C, etc.), anti-inflammatory, caffeine, or alcohol during the experimentation period and one month before participating in any high-intensity sessions before 72 h and during the experimentation period.

Design outcomes

Primary

MeasureTime frame
Physical performance during the 5mSRT:assessed using GPS tracking system heart rate sensors during exercise to record covored distance and peak and mean HR.;Biochemical parameter: • muscle damage markers (creatine kinase (CK), Aspartate transaminase (AST) and Lactate dehydrogenase (LDH)) • plasma concentrations of amino acids (Branched-chain amino acids (BCAA), Leucine (Leu), isoleucine (Ile), and valine (Val));Physical parameters: jump tests;Delayed onset of muscle soreness;Cognitive functions (Digit cancelation test (DCT) and reaction time (RT))

Secondary

MeasureTime frame
Psychological questionnaires: Mood state and the hooper’s index;Sleep quality

Countries

Tunisia

Contacts

Public ContactSami HIDOURI

Research Laboratory Education Motricity Sport and health LR19JS01 High Institute of Sport and Physical Education of Sfax Tunisia

samihidouri4@gmail.com+21627974272

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026