Comparative study of oral clindamycin and metronidazole in the treatment of Bacterial vaginosis in pregnant women attending antenatal clinic in the university of Uyo teaching hospital,Uyo, Akwa Ibom State,Nigeria.

Oral Clindamycin compared with metronidazole in the treatment of Bacterial vaginosis in pregnant women attending antenatal clinic in the university of Uyo teaching hospital,Uyo, Akwa Ibom State, Nigeria

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

PACTR

Registry ID

PACTR202208601005566

Enrollment

130

Registered

2022-08-31

Start date

2022-02-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bacterial vaginosis

Interventions

Oral Clindamycin

Oral metronidazole Group B

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1) Pregnant women attending antenatal clinic in University of Uyo teaching hospital UUTH after booking but before 32weeks GA, the GA determined from their last menstrual period or from an early ultrasound scan dating. 2) Pregnant women willing to give their informed consent. 3) Pregnant women with singleton pregnancies.

Exclusion criteria

Exclusion criteria: 1) Any pregnant woman that refuses or withholds her consent to participate in the study. 2) contraindications or allergies to clindamycin or metronidazole. 3) Use of oral antibiotics or anti fungal agents concurrently, within the last 2.weeks 4) All pregnant women with known obstetrics and or medical complications that could be a precipitating factor for preterm labor or an indication for induction of labor prematurely.

Design outcomes

Primary

Measure	Time frame
Premature rupture of membranes is the spontaneous rupture of fetal membrane before the onset of labor. It can be at term or remote from term.;Preterm labour is the spontaneous onset of uterine contractions, descent of fetal presenting part and cervical changes before 37 weeks GA. ;Low birthweight refers to babies who weigh less Tran 2500grams at birth;Late miscarriage or second trimester miscarriage refers to spontaneous termination of pregnancy that occurs after 12weeks of pregnancy but before age of fetal viability 28weeks;Admission into the Neonatal intensive care unit for any indication	—

Measure

Time frame

Premature rupture of membranes is the spontaneous rupture of fetal membrane before the onset of labor. It can be at term or remote from term.;Preterm labour is the spontaneous onset of uterine contractions, descent of fetal presenting part and cervical changes before 37 weeks GA. ;Low birthweight refers to babies who weigh less Tran 2500grams at birth;Late miscarriage or second trimester miscarriage refers to spontaneous termination of pregnancy that occurs after 12weeks of pregnancy but before age of fetal viability 28weeks;Admission into the Neonatal intensive care unit for any indication

—

Secondary

Measure	Time frame
Maternal post operative complications if delivery was through Caesarean section ;Puerperal complications if delivery was through spontaneous vertex delivery	—

Countries

Nigeria

Contacts

Public ContactOku Okoiseh

Senior Registrar

drokoiseh@yahoo.com+2348061201864

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026