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The effect of Histidine -Tryptophan-Ketoglutarate cardioplegia alone or combined with preoperative infusion of levosimendan on vasoactive inotropic score in patients with poor cardiac function undergoing coronary artery bypass grafting

The effect of Histidine -Tryptophan-Ketoglutarate cardioplegia alone or combined with preoperative infusion of levosimendan on vasoactive inotropic score in patients with poor cardiac function undergoing coronary artery bypass grafting

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
PACTR
Registry ID
PACTR202207785952318
Enrollment
102
Registered
2022-07-08
Start date
2022-06-30
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

levosimendan
normal saline

Sponsors

Maha Elkotb
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: age 40-60 poor cardiac function <40% isolated elective CABG NYHA class ll,lll & lv cross clamp time <120 minutes both sexes

Exclusion criteria

Exclusion criteria: age60 cardiac function >40% severe renal or hepatic disease severe mitral regurge Redo operation complex cardiac surgery patients with preoperative neurological deficits patient refusal

Design outcomes

Primary

MeasureTime frame
vasoactive inotropic score—

Secondary

MeasureTime frame
vasoactive inotropic score at 48 hours , mechanical ventilation by hours ,ICU stay by days ,hospital days and systolic function assessed by transthoracic echocardiography—

Countries

Egypt

Contacts

Public ContactMaha Elkotb

assistant lecturerAin shams university

mahaelkotb@gmail.com01002138557

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026