Efficacy and Safety of Modified Del Nido Cardioplegia in Adult Cardiac Surgeries

Efficacy and Safety of Modified Del Nido Cardioplegia in Adult Cardiac Surgeries: A Randomized Control Trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

PACTR

Registry ID

PACTR202207730603285

Enrollment

Registered

2022-07-14

Start date

2020-11-15

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

Modified Del Nido cardioplegia

Conventional blood crystalloid cardioplegia

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Age 18 years or older Undergoing elective cardiothoracic surgical procedures requiring cardiopulmonary bypass with cross clamp time < 90 min

Exclusion criteria

Exclusion criteria: Patient refusal Known allergy to any of the medications used in this study Patients with coronary artery diseases Patients with ejection fraction < 50% Emergency surgeries Patients on preoperative inotropic support and/or mechanical circulatory support Redo surgeries

Design outcomes

Primary

Measure	Time frame
The rhythm after removal of aortic cross clamp	—

Secondary

Measure	Time frame
Reperfusion rhythm after removal of cross clamp;Potassium level immediately after aortic declamping;The number and the dose of DC shocks;CK, CKMB and Troponin T immediately after declamping.;Need for inotropes or vasopressor support and doses.;Need for anti-arrhythmia medication.;Ventricular ejection fraction change	—

Countries

Egypt

Contacts

Public ContactRadwa Osman

Faculty of Medicine Ain Shams University

radwa.s.osman@gmail.com00201141595674

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026