Nasal High Frequency Oscillatory Ventilation versus Nasal Continuous Positive Airway Pressure as Initial Therapy in Respiratory Distress Syndrome in Preterm Newborns

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

PACTR

Registry ID

PACTR202207646279984

Enrollment

Registered

2022-07-22

Start date

2021-05-01

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neonatal Diseases Respiratory

Interventions

nasal continuous positive airway pressure

nasal high frequency ventilation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Appropriate weight for the gestational age of preterm infants between 280/7 and 336/7 weeks of gestation was determined by the New Ballard Score (Ballard et al., 1991), data from the last menstrual period (LMP) or ultrasound measurement of the fetus. 2. Respiratory distress syndrome diagnosis was made on the basis of the combination of clinical features and radiological features.

Exclusion criteria

Exclusion criteria: • Full-term neonates. • Other causes of respiratory distress than RDS. • Need for intubation for mechanical ventilation during neonatal resuscitation or on the first 2 days of life. • Major congenital malformations. • Intrauterine growth retardation.

Design outcomes

Primary

Measure	Time frame
failure of technique and need of intubation	—

Secondary

Measure	Time frame
duration of noninvasive respiratory support, exposure to invasive ventilation, duration of respiratory support, hospital stay, and partial pressure of carbon dioxide clearance	—

Countries

Egypt

Contacts

Public ContactHamid el sharkawy

professor of pediatrics tanta university

hamedelsharkawy@hotmail.com+201005106898

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026