Pregnancy and Childbirth
Conditions
Interventions
Sponsors
Nnenna S Nweke
Chidebe C Anikwe
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Nulliparae 2. Women who consented to participate in the study 3. Women with fetus in cephalic presentation 4. Singleton fetus with no evidence of maternal or fetal distress. 5. Women with no contraindication to vaginal delivery. 6. Term pregnancies with intact or ruptured membranes 7. Cervical dilatation of 4-5 cm only 8. Spontaneous or induced labour 9. Patients on epidural
Exclusion criteria
Exclusion criteria: 1 Women with abnormal fetal presentation. 2. Women in latent phase of labour. 3. Preterm / term premature rupture of membranes. 4. Antepartum haemorrhage. 5. Those who refused to consent. 6. Previous uterine scar or surgery. 7. Huge fibroid in pregnancy. 8. Multiple gestations. 9. Multiparous or grand multiparous patients. 10. Medical diseases in pregnancy such as severe preeclampsia/eclampsia and others. 11. History of cervical surgery. 12. Hypersensitivity to drotaverine hydrochloride. 13. Any contraindication to vaginal delivery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| •To determine the efficacy of drotaverine hydrochloride versus hyoscine butyl bromide in reducing the duration of first stage of labour among nulliparous women | — |
Secondary
| Measure | Time frame |
|---|---|
| • To determine the rate of cervical dilatation in the first stage of labour, after administration of drotaverine hydrochloride (in one group) and hyoscine butylbromide (in another group). • To determine the side effects of these drugs on the mother and the baby. • To compare the rate of cervical dilatation and side effects to the mother and baby following the use of drotaverine hydrochloride and hyoscine butylbromide. • To compare participants’ satisfaction with the use of drotaverine hydrochloride and hyoscine butyl bromide during labour. | — |
Countries
Nigeria
Contacts
Public ContactNnenna Nweke
Consultant
Outcome results
None listed