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COMPARATIVE EFFECTS OF ADJUNCTIVE PROBIOTICS VERSUS ANTIBIOTICS ON THE EFFICACY OF SUBGINGIVAL SCALING AND ROOT PLANING AMONG ADULTS WITH LOCALIZED PERIODONTITIS IN LAGOS STATE UNIVERSITY TEACHING HOSPITAL

COMPARATIVE EFFECTS OF ADJUNCTIVE PROBIOTICS VERSUS ANTIBIOTICS ON THE EFFICACY OF SUBGINGIVAL SCALING AND ROOT PLANING AMONG ADULTS WITH LOCALIZED PERIODONTITIS IN LAGOS STATE UNIVERSITY TEACHING HOSPITAL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202206830062994
Enrollment
54
Registered
2022-06-01
Start date
2022-06-13
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Health

Interventions

Subgingival scaling and root planing plus hot saline mouthbath
Subgingival scaling and root planing plus Probiotics
Subgingival scaling and root planing plus Antibiotics

Sponsors

DR. NDUGBU CHUKWUEMEKA UZODINMA
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Periodontal pockets of 4 to 5mm affecting at least 4 teeth Clinical attachment loss of 4 to 6mm affecting at least 4 teeth Patients with no underlying systemic diseases between 18 to 59 years of age Chronic gingivitis patients presenting with gingival bleeding on probing

Exclusion criteria

Exclusion criteria: Less than 20 teeth Had subgingival scaling and root planing less than or equal to 6 months prior to the period of recruitment Systemic diseases such as rheumatic heart disease, prosthetic heart valves, diabetes mellitus, hypertension, autoimmune diseases, osteoporosis Patients who have used medications with effect on periodontium such as phenytoin, nifedipine or oral contraceptives within 3 months of the study Currently using formulated mouth rinse agents which can disturb the microbial environment in the oral cavity Pregnant/breast feeding patients Former and current smokers Patients on probiotic supplements within 3 months prior to study and those allergic to probiotics or its lactate contents Mentally/physically handicapped individuals who cannot adhere to oral hygiene instructions

Design outcomes

Primary

MeasureTime frame
Clinical attachment gain which is the decrease in sum of probing pocket depth and gingival recession which will be measured with the University of North Carolina-15 periodontal probe Oral hygiene which will be measured using Community Periodontal Index of Treatment Need-Clinical periodontal probe

Secondary

MeasureTime frame
Plaque Index which will be measured using the Community Periodontal Index of Treatment Needs-Clinical periodontal probe Gingival Index which will be measured using the University of North Carolina-15 periodontalprobe probe

Countries

Nigeria

Contacts

Public ContactMODUPEORE SORUNKE

HEAD OF DEPARTMENT

modupeore.sorunke@lasucom.edu.ng+2348033152418

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026