Oral Health
Conditions
Interventions
mouthwash formulated with Spirulina platensis
Chlorhexidine
Sponsors
PIEME CONSTANT ANATOLE
Alexia Adorance JOTSA
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: - Adult patients (18 years and older), - men or women with: (1) cardiovascular disease; (2) superficial chronic periodontal inflammation: = 2 inter proximal sites with a loss of attachment = 3mm or =2 inter proximal sites with a pocket depth = 4mm (not on the same tooth) or a single site with a depth of pocket = 5mm (CDC-AAP definition of periodontitis); (3) at least 10 teeth in the oral cavity; (4) -All patients gave written informed consent.
Exclusion criteria
Exclusion criteria: - Patients lost to follow-up for 7 days; those who have withdrawn their informed consent; -Patients with cardiovascular diseases (CVD) but with moderate / severe chronic periodontitis; patients with CVD at risk of endocarditis: valve disease, valve prosthesis, interventricular communication, persistent aortic duct; patients taking antibiotics, anti-inflammatories, tobacco; or having an allergy to algae; patients using toothpaste or any other medicament with periodontal action including toothpaste based on sodium bicarbonate; and pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint was the change in periodontal indices | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary endpoints were the change in the level of salivary biochemical markers , pH, Malondialdehyde, Total Antioxidant Capacity | — |
Countries
Cameroon
Contacts
Public ContactArnaud CHOUPO
Faculty of Medicine and Biomedical Sciences University of Yaounde I
Outcome results
None listed