combination of intravenous lidocaine and dexamethasone in reducing the incidence of postoperative sore throat.

Does combination of intravenous lidocaine and dexamethasone reduce the incidence of a postoperative sore throat? A randomized controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

PACTR

Registry ID

PACTR202206603640251

Enrollment

140

Registered

2022-06-10

Start date

2019-07-08

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

intravenous dexamethasone in reducing postoperative sore throat

Combination of intravenous lidocaine and dexamethasone.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1- American Society of Anesthesiologists' physical status (ASA) grades 1 and 2 require general anesthesia with endotracheal intubation 2- Duration of surgery more than 120 min

Exclusion criteria

Exclusion criteria: 1- pre-existing hoarseness of voice or sore throat 2- Smoker 3- Recent or recurrent respiratory tract infection 4- Risk factors for post-operative aspiration 5- Body mass index>35 6- Pregnancy 7- Receiving analgesia, corticosteroids and calcium channel blockers 8- Contraindication to corticosteroid 9- Anticipated difficult intubation and ventilation 10- More than one intubation attempt

Design outcomes

Primary

Measure	Time frame
incidence of postoperative sore throat at rest after surgery	—

Secondary

Measure	Time frame
incidence of postoperative sore throat on swallowing after surgery;incidence of postoperative cough after surgery ;incidence of postoperative hoarseness of voice after surgery	—

Countries

Egypt

Contacts

Public ContactMostafa Abdelkhalek

Lecturer of anesthesia and surgical intensive care. Mansoura university

moustafa.abdelkhale2@mans.edu.eg00201117412903

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026