Hemodynamic and Analgesic Effectiveness of Pre-mixed versus Sequential Administration of Intrathecal Fentanyl with Hyperbaric Bupivacaine for Patients Undergoing Cesarean delivery.

Hemodynamic and Analgesic Effectiveness of Pre-mixed versus Sequential Administration of Intrathecal Fentanyl with Hyperbaric Bupivacaine for Patients Undergoing Cesarean Section at Dilla University Referral Hospital, Southern Ethiopia, 2021: a Randomized Controlled Trial.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

PACTR

Registry ID

PACTR202205853184065

Enrollment

192

Registered

2022-05-09

Start date

2022-04-05

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ceserean section Anaesthesia

Interventions

Bupivacaine

pre mixed hyperbaric bupivacine and by single syringe for spinal anesthesia

sequential administration of hyperbaric bupivacane and fentanyl intratechally

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: The term, ASA II parturients who will undergo elective cesarean delivery under spinal anesthesia

Exclusion criteria

Exclusion criteria: ? Patients with a history of adverse responses to fentanyl or bupivacaine ? Patients with height 175cm ? BMI > 40 kg/m2 ? Multiple pregnancy & macrosomia ? Hypertensive disorders of pregnancy (eclampsia, pre-eclampsia) ? Known diabetic patient ? Mothers on beta-blockers and any other drug which alter the response to study drug ? Baseline heart rate 120beat per minute ? Febrile patient

Design outcomes

Primary

Measure	Time frame
Hemodynamic and Analgesic effectiveness of pre-mixed versus sequential administration of intrathecal fentanyl with hyperbaric bupivacaine among patients undergoing cesarean section	—

Secondary

Measure	Time frame
Associated peri operative complications	—

Countries

Ethiopia

Contacts

Public ContactDaniel Kebede

Lecturer

danielkebede26@yahoo.com+251913804852

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026