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Tranexamic acid versus etamsylate in reducing blood loss in patients with high risk of postpartum hemorrhage

Tranexamic acid versus etamsylate in reducing blood loss during normal vaginal delivery in patients with high risk of postpartum hemorrhage: Randomized controlled trial

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
PACTR
Registry ID
PACTR202205750416982
Enrollment
180
Registered
2022-05-18
Start date
2022-04-01
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post partum hemorrhage

Interventions

tranexamic acid
saline

Sponsors

October 6th university and Ain shams Maternity hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: All pregnant women who will give birth vaginally, full term of gestation age, susceptible for post-partum hemorrhage as: • History of pervious postpartum hemorrhage precipitate labour or instrumental delivery or prolonged induction of labour. •Anemic (hemoglobin between 8-10mg/dl), diabetic, macrosomic baby

Exclusion criteria

Exclusion criteria: Women with thrombophilia, or coagulopathy cardiovascular, renal, or liver disorders; or contraindication to any drug used in the study protocol as (allergy to TXA or its excipients)

Design outcomes

Primary

MeasureTime frame
1) The amount of blood loss measured by using the difference between pre weighted towels and weightof towels soaked with blood ,towels were weighed 2h postpartum Two digital scales of the same brandwill be calibrated by the biomedical engineeringdepartment, one placed in October 6th university hospital and the other one placed in Ain shams Maternity hospital. 2) Complete blood picture (CBC) comparing hematocrit pre and postoperative and clinical data include blood pressure, pulse, andtemperature.

Secondary

MeasureTime frame
The percentage of cases that developed postpartumhemorrhage, the need for blood transfusion and theneed for further interventions to combat postpartum hemorrhage

Countries

Egypt

Contacts

Public ContactHaitham torky

assistant professor

Haithamtorky@yahoo.com01001230161

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 9, 2026