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Effects of ketamine-fentanyl and propofol-fentanyl combinations on LMA insertion conditions in Nigerian children undergoing day-case herniotomy: a randomized controlled trial

Effects of ketamine-fentanyl and propofol-fentanyl combinations on LMA insertion conditions in Nigerian children undergoing day-case herniotomy: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202205734825652
Enrollment
80
Registered
2022-05-04
Start date
2016-01-10
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

None listed

Sponsors

Authors
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: INCLUSION CRITERIA 1. All consenting/assenting patients between the ages of 1 and 15years scheduled for elective herniotomy procedure under general anaesthesia. 2. American Society of Anesthesiologists’ (ASA) physical status class I and II patients.

Exclusion criteria

Exclusion criteria: EXCLUSION CRITERIA 1. Patients with history of allergic reactions to propofol, ketamine and fentanyl. 2. Patient refusal to participate/parent's and guidance failure to give assent. 3. Patients American Society of Anesthesiologists’ (ASA) physical status greater than II. 4. All patients with clinically significant cardiovascular, respiratory, hepatic and renal diseases. 5. Patients currently taking sedative or analgesic drugs. 6. Difficulty with communication/language barrier. 7. Patients with mental illness. 8. Patients with oropharyngeal pathology. 9. Patients with hiatus hernia. 10. Patients with respiratory tract infection. 11. Patients with history of seizure disorder. 12. Patients with raised intracranial or intraocular pressure. 13. Anatomical abnormality of the airway. 14. Patients at risk of aspiration. 15. Patients with hyperactive airway.

Design outcomes

Primary

MeasureTime frame
Laryngeal mask airway insertion conditions and incidence of apnoea were assessed as primary outcome measures

Secondary

MeasureTime frame
Post anaesthetic discharge score was assessed as secondary outcome measure.

Countries

Nigeria

Contacts

Public ContactAkere Abidemi David

Consultant Anaesthetist

demiakere@yahoo.com+2348063103200

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026