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Radiofrequency Ablation of Genicular Nerves in Chronic Knee Osteoarthritis: A Randomized Controlled Trial of Local Anesthetic versus a combination of Local Anesthetic and Corticosteroid to alleviate post procedural neuritis

Radiofrequency Ablation of Genicular Nerves in Chronic Knee Osteoarthritis: A Randomized Controlled Trial of Local Anesthetic versus a combination of Local Anesthetic and Corticosteroid to alleviate post procedural neuritis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202204912139585
Enrollment
60
Registered
2022-04-19
Start date
2019-06-10
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Musculoskeletal Diseases Post Radiofrequency Neuritis

Interventions

Injection of the genicular nerves before radiofrequency

Sponsors

Ain Shams University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: • Age between 50 and 80 years. • Presence of refractory knee pain of at least 3 months duration and at least grade 2 radiographic evidence of OA on the 5-point Kellgren–Lawrence scale. • Numerical Rating Scale (NRS) score at Day 1 = 4 on chronic pain medication and = 6 if not on chronic pain medication. • All patients should have a good response to the diagnostic genicular nerve block.

Exclusion criteria

Exclusion criteria: • Acute knee pain, prior knee surgery, other connective tissue diseases that affected the knee. • Serious neurological or psychiatric disorders. • Steroid, hyaluronic acid injection therapy or electroacupuncture treatment during the previous 12 weeks. • Associated sciatic pain. • Anticoagulant medication use. • Pacemaker use.

Design outcomes

Primary

MeasureTime frame
Reduced or absent intensity of post radiofrequency neuritis with steroids

Secondary

MeasureTime frame
Any complication related to RF ablation such as infection, haemorrhage, thermal injury, loss of motor, and or sensory control in the corresponding area of the involved nerves

Countries

Egypt

Contacts

Public ContactAhmed Elfaioumy

Assistant Lecturer

ahmedsaad_elfaioumy@yahoo.com+447376477170

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026