Evaluation of the safety and efficacy of combination of neostigmine and ketorolac added to reduced local anesthetic mixture dose through medial canthus injection in vitrectomy surgery

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

PACTR

Registry ID

PACTR202204650206424

Enrollment

Registered

2022-04-14

Start date

2022-04-16

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

saline plus peribulbar block anesthesia

neostigmine plus ketorolac

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult patients (aged 25-65 years) Axial length ranging from 20 to 29 Undergoing vitrectomy surgery American Society of Anesthesiologists physical status I or II

Exclusion criteria

Exclusion criteria: Uncooperative patients Patients who cannot lie flat for the duration of the surgery as those with skeletal problems Patients with severe coagulation disorders Patients with bradycardia or bronchial asthma

Design outcomes

Primary

Measure	Time frame
hemodynamic parameters - heart rate, blood pressure, oxygen saturation;Onset of sensory block;Duration of the sensory block;Onset of akinesia;Duration of akinesia	—

Secondary

Measure	Time frame
Surgeon satisfaction;Patient satisfaction;Time of the 1st analgesic dose required and adverse events	—

Countries

Egypt

Contacts

Public ContactIman Sobhy

Department of Anesthesia Research institute of Ophthalmology

iman.sobhy333@gmail.com+201225403093

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026