Anaesthesia
Conditions
Interventions
Group A
Group B
Sponsors
Rania Magdi Ali
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Age: from 1 to 8 years old sex: male and females American Society of Anesthesiologist physical status (ASA-PS) I-II
Exclusion criteria
Exclusion criteria: Children with suspected difficult airway Children with Body Mass Index (BMI) > 30 Children with mental retardation or neurobehavioral disorders History of allergic reactions to Dexmedetomidine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| to evaluate and compare parental separation, 30 minutes after premedication with two different doses of nebulized dexmedetomidine using the parental separation anxiety scales PSAS as follow: 1= easy separation, 2= whimpers, but is easily reassured, not clinging, 3= cries and cannot be easily reassured, but not clinging to parents, and 4= crying and clinging to parents. PSAS scores of 1 and 2 signified calm separation whereas scores of 3 and 4 implied difficult separation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Sedation level was assessed using the Sedation Scale (SS-5). 1= Rarely awake, needs shaking to wake up, 2= Asleep, eyes closed, wake up when lightly touched, 3= Sleepy, but eyes open spontaneously, 4= Awake, and 5= Agitated. The onset of sedation, the minimum time interval necessary to achieve a SS-5 score of 3, and time to Peak sedative effect, the time interval from drug administration to reaching maximum level of sedation, were recorded; Bispectral index (BIS) to measure sedation level. ;Patients Hemodynamics Heart Rate, Mean Arterial Pressure and peripheral O2 saturation SPO2;Ease of venipuncture (EVP) was graded as poor (uncooperative without success), fair (uncooperative with success), good (minor resistance), or excellent (no reaction;Quality of surgical field (QSF) assessed by operating surgeon using QSF score as follow 1 = minimal bleeding: not a surgical annoyance, 2 = mild bleeding: but does not affect dissection, 3 = moderate bleeding: slightly compromises dissection, 4 = severe bleeding: significantly compromises dissection, 5 = massive bleeding: prevent dissection.;Recovery time from discontinuation of anesthesia until child opens his or her eyes and become oriented, was recorded in minutes;Emergence agitation (EA) was assessed in post anesthesia care unit PACU using the Watcha scale as follow 0= Asleep, 1= Calm, 2= Crying, but can be consoled, 3= Crying, but cannot be consoled, 4= Agitated and thrashing around. Score more than 2 indicates the presence of EA;Adverse events such as hypotension (MABP reduction greater than 20% from baseline value) requiring fluid bolus administration, bradycardia (defined as HR< 100 bpm in patients 1-3 years old and <60 beats/min in patients 3-8 years old) requiring atropine administration, hypoxemia (defined as SpO2 <90%), the occurrence of postoperative shivering and postoperative nausea and vomiting were noted. | — |
Countries
Egypt
Contacts
Public ContactRania Magdi Ali
Assistant Professor of Anesthesia intensive care and Pain management faculty of medicine Ain Shams university
Outcome results
None listed