Analgesic and hemodynamic effects of intravenous magnesium sulfate infusion versus lidocaine infusion in patients undergoing thyroid surgery for toxic goiter resection

Analgesic and hemodynamic effects of intravenous magnesium sulfate infusion versus lidocaine infusion in patients undergoing thyroid surgery for toxic goiter resection: a randomized controlled study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202204562765688

Enrollment

Registered

2022-04-14

Start date

2022-04-18

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

Lidocaine Group

Mg So4 Group

Control Group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ?-patients of both sex ?- Aging from 20-60 years ?- Patients with primary or secondary thyrotoxic goiter. ?- American Society of Anesthesiologists (ASA) classes I or II

Exclusion criteria

Exclusion criteria: ? Major hepatic disease ? Renal disease. ? Cardiac dysfunction e.g. (Heart Failure). ? Uncontrolled hypertension ? Advanced Ischemic heart diseases. ? Known allergy to Mg So4. ? Morbid obesity & pregnancy. ? History of neuromuscular diseases. ? Cerebrovascular diseases. ? Diabetic neuropathy. ? Patients receiving magnesium supplementations. ? Mental retardation ? Patients on antiepileptic treatment ? Patient's on antipsychotics. ? Huge goiter with retrosternal extension

Design outcomes

Primary

Measure	Time frame
Post-operative pain measured by VAS score;Hemodynamic parameters (mean arterial blood pressure and heart rate)	—

Secondary

Measure	Time frame
Time of first analgesic request.;Total opioid consumption postoperative	—

Countries

Egypt

Contacts

Public ContactAhmed Sakr

Lecturer of general surgery

ahmadsakr1987@gmail.com01004421980

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026