A study to improve Gentamicin antibiotic prescription accuracy during hospital care for sick new-born babies in Kenya over time using feedback given to clinicians

Conditions

Neonatal care prescribing practices

Timothy Tuti, Jalemba Aluvaala, Mercy Mulaku, Dorothy Aywak, Muthoni Ogola et al. (7 authors)

Implementation Science Communications2026-09-05

Evaluation of a pharmacist-led audit and feedback intervention to reduce Gentamicin prescribing errors at admission in neonatal inpatient care in Kenya: A controlled interrupted time series study

Timothy Tuti, Jalemba Aluvaala, Mercy Mulaku, Dorothy Aywak, Muthoni Ogolla et al. (7 authors)

2026-01-30

10.64898/2026.01.27.26345018

Evaluation of an audit and feedback intervention to reduce gentamicin prescription errors in newborn treatment (ReGENT) in neonatal inpatient care in Kenya: a controlled interrupted time series study protocol

Timothy Tuti, Jalemba Aluvaala, Lucas Malla, Grace Irimu, George Mbevi et al. (100 authors)

Implementation Science2022-05-165 citations

10.1186/s13012-022-01203-w

Interventions

Package I

Package II

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Referral-level hospitals with: (1) high quality gentamicin prescription baseline clinical data for neonatal inpatient care and, (2) a standardised A&F routine clinical improvement cycle to track prescribing practices in neonatal inpatient care are eligible for inclusion in this study. All neonates admitted to the newborn units in these hospitals with a gentamicin prescription at admission will be included in the study.

Exclusion criteria

Exclusion criteria: Referral-level hospitals without 12 months worth of high quality gentamicin prescription baseline clinical data for neonatal inpatient care and without a standardised A&F routine clinical improvement cycle to track prescribing practices in neonatal inpatient care are not eligible for inclusion in this study. All neonates admitted to the newborn units in these hospitals with missing data on gentamicin prescription at admission will be excluded from this study.

Design outcomes

Primary

Measure	Time frame
The primary outcome of this study being measured is the proportion of patients in newborn units receiving an inaccurate Gentamicin prescription over time (i.e., incidence rate ratio)	—

Secondary

Measure	Time frame
Relative difference in the proportion of patients in newborn units receiving an inaccurate Gentamicin prescription over time (i.e., incidence rate ratio) due to Audit and Feedback package received.	—

Countries

Kenya

Contacts

Public ContactGeorge Mbevi

Study Project Coordinator

GMbevi@kemri-wellcome.org+254728787731

Outcome results

None listed