Malaria
Conditions
Sponsors
Academic Medical Centre at the University of Amsterdam
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Gestation =16 weeks and <37 weeks as assessed by ultrasound when possible, uterine height or late menstrual period; 2. Age: =18 years (DRC) or Age: =15 years (Burkina Faso); 3. Residence within the health facility catchment area; 4. Ability to provide written informed consent.
Exclusion criteria
Exclusion criteria: 1. Not meeting the above criteria 2. Known history of allergy to SP or to an ACT 3. An ongoing antibioprophylaxis with cotrimoxazole, 4. Current issue requiring hospital admission (including severe malaria as defined by WHO) 5. Pregnancy at high risk.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sensitivity, specificity, negative and positive predictive values of mini-dbPCR-NALFIA test to detect malaria infection in pregnant women compared to routine diagnostic procedures in place | — |
Secondary
| Measure | Time frame |
|---|---|
| To determine the utility of the mini-dbPCR-NALFIA test in monitoring treatment efficacy, parasite clearance will be assessed by mini-dbPCR-NALFIA and compared with qPCR Burkina Faso;sensitivity, specificity, negative and positive predictive values of mini-dbPCR-NALFIA test compared to ultra sensitive RDT for the diagnosis of malaria in pregnant women DRC | — |
Countries
Burkina Faso, Democratic Republic of the Congo
Contacts
Public ContactPetra Mens
Senior scientist Malaria
Outcome results
None listed