timing of metformi administration and exercise

Effect of pre-meal metformin with or without an acute exercise bout on postprandial lipemia in metabolic syndrome patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202203690920424

Enrollment

Registered

2022-03-28

Start date

2022-02-24

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nutritional, Metabolic, Endocrine

Interventions

Administration of Metformin with a test meal

Administration of Metformin 30 minutes prior to a test meal

Acute exercise with metformin administred 30 minutes prior to a test meal in the next day

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ?Increased waist circumference (=102 cm in men; =88 cm in women) ?Elevated triglycerides (=150 mg/dl), or on medication for treating the condition ?Reduced HDL-cholesterol (<40mg/dl in men, <50 mg/dl in women), or on medication for treating the condition ?High blood pressure (=130 mmHg systolic or =85mmHg diastolic), or on medication for treating the condition ?Elevated fasting glucose (=100 mg/dl), or on medication for treating the condition

Exclusion criteria

Exclusion criteria: Any condition that counter-indicate exercise Patients under glucose lowering agents

Design outcomes

Primary

Measure	Time frame
Postprandial triglycerides	—

Secondary

Measure	Time frame
Total cholesterol;LDL-cholesterol;HDL-Cholesterol;Glucose;Insulin;Metformin side effects;Perceived appetite sensations	—

Countries

Tunisia

Contacts

Public ContactJabeur Methnani

Researcher

jabeur.methnani@gmail.com+21693201456

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026