Adding of midazolam to bupivacaine versus bupivacaine alone in combined sciatic and saphenous nerve block at knee in anaethesia of foot and ankle surgeries.

Effect of adding midazolam in ultrasound guided combined sciatic and saphenous nerve block at knee for anaethesia of foot and ankle surgeries.

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

PACTR

Registry ID

PACTR202203606484149

Enrollment

Registered

2022-03-30

Start date

2022-02-14

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery Orthopaedics Anaesthesia

Interventions

combined sciatic and saphenous nerve block by bupivacaine and midazolam

combined sciatic and saphenous nerve block by bupivacaine only

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patient aged between 20 and 75 yaers years both genders who schedule for foot and ankle surgeries and ASA I to III

Exclusion criteria

Exclusion criteria: Patient younger than 20 years or older than 75 years and patient who allergy to local anaethetics or to midazolam and who had past history of sciatic or saphenous nerve inury and who have neurological or rheumatological or psychiatric diseases.

Design outcomes

Primary

Measure	Time frame
by compare onset of succesful block before operation by complete loss of sensation to pinprick in below knee area chosen as the successful end point between two groups. and duration of block in intraoperative and postoperative period by visual analogue scale and rescue analgesia between two groups .VAS Scale (1-10) Zero was considered as no pain, 1-3 as mild pain, 4-6 as moderate pain and 7-10 as severe pain. At score of 4 rescue analgesic.Duration of sensory block was defined as the time interval between the success of the block and the complete resolution of sensory block or first analgesia rescue and the time was recorded.	—

Measure

Time frame

by compare onset of succesful block before operation by complete loss of sensation to pinprick in below knee area chosen as the successful end point between two groups. and duration of block in intraoperative and postoperative period by visual analogue scale and rescue analgesia between two groups .VAS Scale (1-10) Zero was considered as no pain, 1-3 as mild pain, 4-6 as moderate pain and 7-10 as severe pain. At score of 4 rescue analgesic.Duration of sensory block was defined as the time interval between the success of the block and the complete resolution of sensory block or first analgesia rescue and the time was recorded.

—

Secondary

Measure	Time frame
assess motor function by Bromage motor blockade score in which Free movement of legs and feet means no motor block and Just able to flex knees with free movement of feet means Partial (33%) block and Unable to flex knees, but with free movement of feet means almost complete (66%)and Unable to move legs or feet means Complete (100%) block between two groups.	—

Countries

Egypt

Contacts

Public ContactHend Sallama

neurological specialist

hamadahafez@gmail.com00201021385636

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026