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Ondansetron versus Acetaminophen for Prevention of Postspinal Anesthesia Shivering in Cesarean Section: A Randmized Controlled Trial

Ondansetron versus Acetaminophen for Prevention of Postspinal Anesthesia Shivering in Cesarean Section: A Randmized Controlled Tria

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
PACTR
Registry ID
PACTR202203547348725
Enrollment
90
Registered
2022-03-04
Start date
2021-08-17
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

Sponsors

Anesthesia department
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: ASA physical status II female patients, 18-40 years old scheduled for caesarean section under spinal anesthesia.

Exclusion criteria

Exclusion criteria: fever or hypothermia before the procedure. History of hypertension, cardiovascular, psychiatric, neurological, endocrine, chest disease, and/or severe renal or hepatic dysfunction . obese patients (BMI =30 kg/m2) those who will need intraoperative blood transfusion those with known allergy to any of this study drugs. Any contraindication to neuraxial block

Design outcomes

Primary

MeasureTime frame
occurrence of shivering The shivering severity will be graded as: grade 1(piloerection or peripheral cyanosis, but without visible muscle activity), grade 2 (visible muscle activity confined to one muscle group), grade 3(visible muscle activity in more than one muscle group), or grade 4 (gross muscle activity involving the whole body).Any shivering attack with a score >2 will be treated with Meperidine 25 mg IV. Shivering will be analysed for incidence (number of attacks), severity, time to occur after the intrathecal anesthetic, and its response to meperidine administration.

Secondary

MeasureTime frame
totally received meperidine doses, the time for first postoperative analgesia request, the occurrence of hypotention or bradycardia, the perioperative complications (nausea, vomiting, dry mouth, dizziness, and desaturation).

Countries

Egypt

Contacts

Public ContactAsmaa Hamza

Lecturer of anesthesia

asmaa_6october@yahoo.com0020482228305

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026