A comparison between propofol, dexmeditomedine and nitroglycerin as hypotensive agents and their effect on blood loss in functional endoscopic sinus surgery (FESS)

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

PACTR

Registry ID

PACTR202202877370804

Enrollment

Registered

2022-02-09

Start date

2019-08-12

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

Group P

Group D

Group N

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: both sexes aging 20-50 years old ASA physical status I – II

Exclusion criteria

Exclusion criteria: -Patient refusal -Pregnant females -Patients with pulmonary diseases, ischemic cardiovascular disease, ischemic cerebrovascular disease, hepatic disease, renal disease, diabetes mellitus, coagulopathies /and anemia -Patients with uncontrolled hypertension -patients with first, second or third heart block

Design outcomes

Primary

Measure	Time frame
The primary outcome measurement was to compare the efficacy of dexmedetomidine , propofol and nitroglycerine in inducing controlled hypotension and the time needed in every group to obtain the targeted blood pressure.	—

Secondary

Measure	Time frame
The secondary outcome measurements were controlling heart rate, inducing bloodless surgical field for better exposure and shorter duration of surgery during FESS.	—

Countries

Egypt

Contacts

Public ContactMohamed;Adel Elshorbagy;Shenoda

lecturer of anesthiology at faculty of medicine Ain Shams university;professor of anestiology at faculty of medicine Ain Shams university

dr.mohammedelshorbagy@gmail.com;amikhaeal@hotmail.com00201227528857;00201227817112

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026