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Comparison between Combined regional nasal block and general anesthesia versus general anesthesia with dexmedetomidine during endoscopic sinus surgery

Comparison between Combined regional nasal block and general anesthesia versus general anesthesia with dexmedetomidine during endoscopic sinus surgery

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
PACTR
Registry ID
PACTR202201855749323
Enrollment
70
Registered
2022-01-10
Start date
2021-04-15
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

Sponsors

Faculty of medicine Ain shams university
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion Criteria: 1) Patients of ASA I or ASA II physical status. 2) Patients with age 18-65 years.

Exclusion criteria

Exclusion criteria: Exclusion Criteria: 1) Patients with physical status ASA III, IV. 2) Known allergic reactions to local anesthetics. 3) Patients with history for cerebrovascular or coronary insufficiency. 4) Patients with infection at the block site. 5) Patients with coagulopathy.

Design outcomes

Primary

MeasureTime frame
Comparison between efficacy of the two techniques in optimizing intraoperative surgical field using the average category scale(ACS).

Secondary

MeasureTime frame
1) The HR and MAP will be measured at the commencement of surgery and at each assessment of the surgical field. The average mean values during the surgical procedures will be calculated in each group. 2) Blood loss will be measured in millilitres as that collected in the suction apparatus and by weight of the nasal swabs. 3) Endtidal sevoflurane concentration will be used as an indicator of inhaled anaesthetic dose. Mean end-tidal sevoflurane concentration will be calculated for each patient as the average of all concentrations recorded. 4) The total dose of additional hypotensive agent (phentolamine) requirements. 5) Duration of anesthesia and surgery will be obtained. 6) Pain intensity will be evaluated with a 10-cm VAS (where 0 is defined as no pain at all and 10 as the worst possible pain)

Countries

Egypt

Contacts

Public ContactMoustafa Atef Moustafa Hamouda

Assistant lecturer department of anesthesia faculty of medicine Ain shams university

moustafaatef.13b@gmail.com+201061123460

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026