School-aged follow-up of the Sanitation, Hygiene, Infant Nutrition Efficacy (SHINE) Cluster Randomised Trial

Conditions

Nutritional, Metabolic, Endocrine

Piper JD, Mazhanga C, Mwapaura M, Mapako G, Mapurisa I, Mashedze T, Munyama E, Kuona M, Mashiri T, Sibanda K, Matemavi D, Tichagwa M, Nyoni S, Saidi A, Mangwende M, Mbewe G, Chidhanguro D, Mpofu E, Tome J, Mutasa B, Chasekwa B, Njovo H, Nyachowe C, Muchekeza M, Sauramba V, Gladstone MJ, Wells JC, Allen E, Moulton LH, Smuk M, Humphrey JH, Langhaug LF, Tavengwa NV, Ntozini R, Prendergast AJ.

2024-11-221 citations

10.1016/j.eclinm.2024.102946

Growth, physical, and cognitive function in children who are born HIV-free: School-age follow-up of a cluster-randomised trial in rural Zimbabwe

Joseph Piper, Clever Mazhanga, Marian Mwapaura, Gloria Mapako, Idah Mapurisa et al. (36 authors)

PLoS Medicine2024-10-114 citations

10.1371/journal.pmed.1004347

The Sanitation Hygiene Infant Nutrition Efficacy (SHINE) Trial: Protocol for school-age follow-up.

Piper JD, Mazhanga C, Mwapaura M, Mapako G, Mapurisa I, Mashedze T, Munyama E, Kuona M, Mashiri T, Sibanda K, Matemavi D, Tichagwa M, Nyoni S, Saidi A, Mangwende M, Chidhanguro D, Mpofu E, Tome J, Mutasa B, Chasekwa B, Smuk M, Smith LE, Njovo H, Nyachowe C, Muchekeza M, Mutasa K, Sauramba V, Langhaug LF, Tavengwa NV, Gladstone MJ, Wells JC, Allen E, Humphrey JH, Ntozini R, SHINE Follow-up team, Prendergast AJ.

2023-07-147 citations

10.12688/wellcomeopenres.19463.1

Interventions

IYCF

WASH

Standard of care

IYCF WASH

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - Enrolled in SHINE and had primary outcome measurement at 18 months of age - Mother tested and HIV status known in pregnancy - Written informed consent of parent / guardian - Age 7 years (defined as between 7 years and 7 years + 364 days of age) - Resident in Shurugwi district

Exclusion criteria

Exclusion criteria: - 8 years of age - Not resident in Shurugwi district

Design outcomes

Primary

Measure	Time frame
Mental processing index MPI from Kaufmann Assessment Battery for Children KABC-2;Mental processing index MPI from Kaufmann Assessment Battery for Children KABC-2	—

Secondary

Measure	Time frame
Total of Writing Reading and Arithmetic Test score;Fine motor from Total time to complete finger tapping task;Plus EF executive function score;Height, weight, head circumference, MUAC;Kaufmann subtest scores, SAT subtest scores, individual fine motor scores, Plus-EF subtest scores and reaction times;Bioimpedance-based lean mass index, phase angle;Sum of skinfold thickness;Knee- heel length;Waist circumference, calf circumference 7year only, ;Subscapular, triceps, suprailiac and calf skinfold thicknesses;Average grip strength for both hands;Grip strength in dominant and non-dominant hand;Broad jump distance;Shuttle run test level;Composite outcome of combined standardised scores of grip strength, broad jump and shuttle run test;Resting blood pressure and blood pressure 1 minute after exercise;Haemoglobin level;Acute illnesses in school age health and visits to traditional healer, clinic and hospital;Annual monitoring visits that measure child growth, body composition, handgrip strength, literacy, numeracy and executive function. ;Child Socioemotional scale;Total of Writing Reading and Arithmetic Test score;Fine motor from Total time to complete finger tapping task;Plus EF executive function score;Height, weight, head circumference, MUAC;Kaufmann subtest scores, SAT subtest scores, individual fine motor scores, Plus-EF subtest scores and reaction times;Bioimpedance-based lean mass index, phase angle;Sum of skinfold thickness;Knee- heel length;Waist circumference, calf circumference 7year only, ;Subscapular, triceps, suprailiac and calf skinfold thicknesses;Average grip strength for both hands;Grip strength in dominant and non-dominant hand;Broad jump distance;Shuttle run test level;Composite outcome of combined standardised scores of grip strength, broad jump and shuttle run test;Resting blood pressure and blood pressure 1 minute after exercise;Haemoglobin level;Acute illnesses in school age health and visits to traditional healer, clinic and hospital;Annual monitorin	—

Measure

Time frame

Total of Writing Reading and Arithmetic Test score;Fine motor from Total time to complete finger tapping task;Plus EF executive function score;Height, weight, head circumference, MUAC;Kaufmann subtest scores, SAT subtest scores, individual fine motor scores, Plus-EF subtest scores and reaction times;Bioimpedance-based lean mass index, phase angle;Sum of skinfold thickness;Knee- heel length;Waist circumference, calf circumference 7year only, ;Subscapular, triceps, suprailiac and calf skinfold thicknesses;Average grip strength for both hands;Grip strength in dominant and non-dominant hand;Broad jump distance;Shuttle run test level;Composite outcome of combined standardised scores of grip strength, broad jump and shuttle run test;Resting blood pressure and blood pressure 1 minute after exercise;Haemoglobin level;Acute illnesses in school age health and visits to traditional healer, clinic and hospital;Annual monitoring visits that measure child growth, body composition, handgrip strength, literacy, numeracy and executive function. ;Child Socioemotional scale;Total of Writing Reading and Arithmetic Test score;Fine motor from Total time to complete finger tapping task;Plus EF executive function score;Height, weight, head circumference, MUAC;Kaufmann subtest scores, SAT subtest scores, individual fine motor scores, Plus-EF subtest scores and reaction times;Bioimpedance-based lean mass index, phase angle;Sum of skinfold thickness;Knee- heel length;Waist circumference, calf circumference 7year only, ;Subscapular, triceps, suprailiac and calf skinfold thicknesses;Average grip strength for both hands;Grip strength in dominant and non-dominant hand;Broad jump distance;Shuttle run test level;Composite outcome of combined standardised scores of grip strength, broad jump and shuttle run test;Resting blood pressure and blood pressure 1 minute after exercise;Haemoglobin level;Acute illnesses in school age health and visits to traditional healer, clinic and hospital;Annual monitorin

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Countries

Zimbabwe

Contacts

Public ContactVirginia Sauramba

Research Administration and Compliance Manager

v.sauramba@zvitambo.com+263242306028

Outcome results

None listed