Pregnancy and Childbirth
Conditions
Interventions
carbetocin
Oxytocin misoprostol combination
Sponsors
sofiat ayobami yusuf
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. All consenting pregnant women undergoing elective or emergency Caesarean section 2. Failed induction of labour 3. Pregnant women with obstructed labour 4. Pregnant women with antepartum haemorrhage secondary to placenta previae 5. Two or more Caesarean section 6. Grand multiparous women
Exclusion criteria
Exclusion criteria: 1. Those who were not counselled because of the emergency nature of their surgery 2. Pregnant women with uterine rupture 3. Pregnant women with bleeding disorders 4. Women receiving general anaesthesia for surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine Efficacy of use of oxytocin-misoprostol combination and carbetocin in reducing blood loss at Caesarean section. To determine the average blood loss at surgery between the two study group. To determine the need for additional uterotonic agents between the two study group. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the rate of postpartum haemorrhage between both groups and need for blood transfusion, to determine the differences in haematocrit concentration 12hours before and 48hours after surgery, to compare the adverse effects of the medication between the two group | — |
Countries
Nigeria
Contacts
Public ContactAdedapo Ande
professor of obstetrics and gynaecology
Outcome results
None listed