Digestive System
Conditions
Interventions
lactated ringer alone
indomethacin
indomethacin and lactated ringer
Sponsors
Mohammed seghir nekache hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: historical criterion of high risk for PEP before the procedure. major criteria included 1 of the following: suspicion for sphincter of Oddi dysfunction, personal history of PEP, more than 8 cannulation attempts, precut sphincterotomy, endoscopic papillary balloon dilation of an intact sphincter, endoscopic PD sphincterotomy. Patients were also included if they met 2 or more of the following minor criteria: female sex and age under 50 years, personal history of recurrent acute pancreatitis, PD injection leading to “acinarization” or over 3 PD injections, and PD cytology acquisition.
Exclusion criteria
Exclusion criteria: age under 18 years, pregnancy, active acute pancreatitis. true documented allergy to or use in the day of the procedure of NSAIDs, acute renal failure, active peptic ulcer disease. Contraindications to aggressive IVF hydration.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary study outcome was Post ERCP Pancreatitis | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes included severe acute pancreatitis (persistent organ failure ! 48 hours), localized AEs (pseudocyst formation, abscess, walled of pancreatic necrosis), death, length of hospital stay in days, and readmission within 30 days. All patients were kept in the recovery area for 4 hours after completion of their ERCP, participants received a telephone call within 24 hours and also at 30 days from their procedure. | — |
Countries
Algeria
Contacts
Public ContactKhellaf AMALOU
Professor in gastroenterology
Outcome results
None listed