Circulatory System Cardiology Anaesthesia
Conditions
Interventions
Low dose amiodarone
Control
Sponsors
faculty of medicine ain shams unversity
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: · All elective isolated cases undergoing mitral valve replacement with a preoperative atrial fibrillation rhythm > 100/min as evidenced by ECG. · ASA physical status 2-5 · Sex (males and females) · Age 18-70 years.
Exclusion criteria
Exclusion criteria: · Patients are refusing to participate in the study. · Below 18 or above 60 years. · Emergency and urgent patients. · Patients are undergoing combined valve or CABG surgery. · Patients with previous PCI. · Patients with rhythm defects evidenced by ECG. · Patient on amiodarone or other rhythm modifying drugs, e.g., Digoxin, Beta Blockers, CCBs, etc. · Patients with preoperative lung conditions or O2 saturation below 90%. · Patients with preoperative abnormal hepatic profiles identified by double average values of ALT/AST or bilirubin or hypoalbuminemia · Patients with preoperative renal impairment identified by serum creatinine more than 1.7 mg/dL · Abnormal thyroid profile or any history suggestive of thyroid diseases. · Diabetic patients, as the study, include Dextrose 5% based medication.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Observe persistence of AF at the end of surgery and document rhythm before transfer to ICU. | — |
Secondary
| Measure | Time frame |
|---|---|
| Initial repercussion rhythm shortly after declamping will be recorded, whether ventricular fibrillation, normal sinus rhythm, or AF ;§ Heart rate and rhythm 10, 30, 60 minutes after de-clamping. ;§ Recurrence of AF during the hospital stay. ;Need for epicardial pacing. | — |
Countries
Egypt
Contacts
Public ContactFarouk Kamal
lecture of anesthesia faculty of medicine ain shams university
Outcome results
None listed