Magnesium Sulphate Loading Dose Only versus Standard Pritchard Regimen in the Management of Eclampsia – A Multi-centre Randomized Clinical Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202201609390328

Enrollment

Registered

2022-01-06

Start date

2016-02-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth

Interventions

Pritchard Loading Dose of MgSO4 only

Standard Pritchard Regimen

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Pregnant women with Eclampsia Women within 10days post-partum with eclampsia

Exclusion criteria

Exclusion criteria: chronic renal failure history of epilepsy received magnesium sulphate and/or other anticonvulsant prior to presentation at the study hospital known contraindication to magnesium sulphate therapy (like myasthenia gravis) intrauterine fetal death if woman or her next-of-kin was not willing or able to give informed consent

Design outcomes

Primary

Measure	Time frame
Rate of recurrence of at least 1 convulsion episode	—

Secondary

Measure	Time frame
Duration of hospital admission post-intervention, need for admission of newborn into neonatal intensive care unit, rate of occurrence of MgSO4-related flushing, pain at injection site	—

Countries

Nigeria

Contacts

Public ContactAyokunle Olumodeji

Obstetrician and Gynecologist

ayokunleolumodeji@yahoo.com+2348032751080

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026