Fetomaternal
Conditions
Interventions
Use of sublingual or rectal misoprostol prior to elective caesarean section
Use of sublingual or rectal misoprostol after elective caesarean section
Sponsors
Prof. HU Ezegwui
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Every consenting pregnant woman who harbours a singleton pregnancy at 37-41 weeks gestational age and do not have any medical disorder will be included in the study. The participants will also receive regional anaesthesia before the caesarean delivery.
Exclusion criteria
Exclusion criteria: This comprised hypertensive disease in pregnancy, multiple gestation, diabetes mellitus, asthma, sickle cell anaemia, liver disease, cardiac disorder, preterm delivery, gestational age beyond 41 weeks gestation ,cases booked for emergency caesarean section, allergy to prostaglandins, general anaesthesia and refusal to give consent to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative blood loss. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Occurrence of primary postpartum haemorrhage ( bleeding of more than 1000mls within 24 hours after caesarean section). 2. Use of extra uterotonics 3. Use of blood transfusion 4. Occurrence of shivering, pyrexia (>38°C), headache, nausea, vomiting with or without the need for anti-emetic drugs within 6 hours after rectal misoprostol insertion. 5. Neonatal outcomes -1st and 5th minutes APGAR scores and admission into neonatal intensive care unit. | — |
Countries
Nigeria
Contacts
Public ContactMonique Ajah
Assistant Research Fellow
Outcome results
None listed