Digestive System
Conditions
Interventions
Optimized sequential therapy
Fourteen day quadruple therapy
Ten days quadruple therapy
Sponsors
Gastroenterology Department of Mohamed V Military Teaching Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: adult patients with Helicobacter Pylori infection confirmed by histological analysis of gastric biopsies taken during upper endoscopy
Exclusion criteria
Exclusion criteria: Patients who previously received eradication therapy, proton pump inhibitors (PPIs), H2 inhibitors, NSAIDs or bismuth compounds 4 weeks before the study and / or who were allergic to prescribed drugs will be excluded. of the study. In addition, pregnant and breastfeeding women as well as patients having undergone gastric surgery, renal or hepatic insufficiency or serious psychiatric disorders will also be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Helicobacter Pylori eradication (by 13C urea breath test) | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse effects of therapy (diarrhea, nausea and / or vomiting, gastralgia, metallic taste, dysgeusia, symptoms related to an allergic reaction, headache, dizziness, asthenia or any other AE.);compliance | — |
Countries
Morocco
Contacts
Public ContactSanaa Berrag
Gastroenterologist of Department of Gastroenterology and Gastrointestinal Endoscopy II Mohamed V Military teaching Hospital
Outcome results
None listed