Analgesic Efficacy of Ultrasound Guided Erector Spinae Plain Block Versus Serratus Anterior Plain Block Using Bupivacaine-Dexamethasone for Patients Undergoing Modified Radical Mastectomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202110546411428

Enrollment

Registered

2021-10-12

Start date

2020-12-15

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer

Interventions

serratus anterior plane block

ESPB

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Female patient aged between 20 and 70 years of American Society of Anesthesiologists physical status (ASA) grades I to III undergoing elective unilateral modified radical mastectomy.

Exclusion criteria

Exclusion criteria: 1. Patient refusal. 2. Neuromuscular diseases (as myopathies, myasthenia gravies…) 3. Hematological diseases, bleeding or coagulation abnormality. 4. Psychiatric diseases. 5. Local skin infection and sepsis at site of the block. 6. Known allergy to the study drugs. 7. Body Mass Index >40 Kg/m2.

Design outcomes

Primary

Measure	Time frame
The time to the first analgesic request in hours (duration of analgesia) was recorded.?	—

Secondary

Measure	Time frame
while the secondary outcomeThe hemodynamics parameters including Heart rate (HR), Mean arterial pressure (MAP) and Peripheral capillary oxygen saturation (SpO2) were recorded basal, after skin incision, 15 min., 30min., then every 30min. intraoperatively. Then in PACU immediately then at 2, 4, 8, 12, 16 and 24 hours post-operatively in the ward. ? Intraoperative total fentanyl consumption. ? Visual analogue scale score would be recorded at 0, 2, 4, 8, 12, 16 and 24 hours post-operatively at rest and movement (arm abduction). ? Total analgesics required in 24 h postoperatively: Fentanyl, paracetamol. ? Any adverse effects related to the regional anesthetic technique would be also documented such as hypotension and bradycardia, inadvertent spinal injection, neurological manifestations, epidural hematoma, intravascular injection ? Surgeon satisfaction confirming analgesia and procedures by Bajwa S et al (Bajwa S et al.,2014). ? Excellent ? Good ? Fair ? Poor ? patient satisfaction confirming analgesia and procedures by Bajwa S et al (Bajwa S et al.,2014). ? extremely satisfied ? satisfied ? not satisfied	—

Measure

Time frame

while the secondary outcomeThe hemodynamics parameters including Heart rate (HR), Mean arterial pressure (MAP) and Peripheral capillary oxygen saturation (SpO2) were recorded basal, after skin incision, 15 min., 30min., then every 30min. intraoperatively. Then in PACU immediately then at 2, 4, 8, 12, 16 and 24 hours post-operatively in the ward. ? Intraoperative total fentanyl consumption. ? Visual analogue scale score would be recorded at 0, 2, 4, 8, 12, 16 and 24 hours post-operatively at rest and movement (arm abduction). ? Total analgesics required in 24 h postoperatively: Fentanyl, paracetamol. ? Any adverse effects related to the regional anesthetic technique would be also documented such as hypotension and bradycardia, inadvertent spinal injection, neurological manifestations, epidural hematoma, intravascular injection ? Surgeon satisfaction confirming analgesia and procedures by Bajwa S et al (Bajwa S et al.,2014). ? Excellent ? Good ? Fair ? Poor ? patient satisfaction confirming analgesia and procedures by Bajwa S et al (Bajwa S et al.,2014). ? extremely satisfied ? satisfied ? not satisfied

—

Countries

Egypt

Contacts

Public ContactMahmoud Alseoudy

drs3oody.mansoura@mans.edu.eg00201006224551

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026