Anaesthesia
Conditions
Interventions
dexmedetomidine
The lidocaine group
Sponsors
Ain Shams Univeristy Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: • Patients (age 21-55 years) • With body mass index (BMI) 18-25 Kg/m2. • ASA 1 and ASA 2 patients • Adequate cognitive state (able to understand and collaborate). • Patients that will undergo elective open abdominal surgery
Exclusion criteria
Exclusion criteria: • Hypersensitivity to any of the used drugs • Pregnancy and lactating mothers • Chronic pain requiring daily use of opioid medication or chronic alcohol abuser • Sleep apnea syndrome. • Bradycardia (heart rate of fewer than 50 beats per min at rest) or patients on beta-blockers or alpha 2 agonists. • Epilepsy or chronic daily use of psychiatric medication • Patients received any other regional anesthesia technique (epidural, transverse abdominis plane (TAP) and Plexus block) • Re-exploration cases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total dose consumption of intraoperative opioids | — |
Secondary
| Measure | Time frame |
|---|---|
| • Postoperative VAS score. • Time of the first rescue of analgesics • Total consumption of pethidine in the 24 hours. • vital signs ( heart rate, non-invasive arterial blood pressure, respiratory rate) • Number of episodes of nausea, vomiting (treated by IV bolus of metoclopramide 10 mg). • Time of return bowel movement, flatus. | — |
Countries
Egypt
Contacts
Public ContactMaha Sadek
Lecturer
Outcome results
None listed