Anaesthesia
Conditions
Interventions
Group HTK
Group HHB
Sponsors
Faculty of medicine at Ain Shams university
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Acyanotic congenital heart diseases undergoing total repair under cardiopulmonary bypass. Aged from 6 months to 2 years of both sexes. Scheduled for elective operations.
Exclusion criteria
Exclusion criteria: Reoperation. Scheduled for palliative surgeries. Undergoing emergency surgeries. Patients with reduced left ventricular function, determined by left ventricular ejection fraction less than 40%. Patients with renal or liver impairment, determined by elevated creatinine levels or liver enzymes ‘AST and ALT’ more than normal values for age. Patients with any neurological dysfunction as epilepsy and cerebral palsy (CP).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Level of Troponins | — |
Secondary
| Measure | Time frame |
|---|---|
| The left ventricular ejection fraction (EF %).;The left ventricular fractional shortening FS.;The maximum vasoactive inotropic score VIS. The VIS was calculated according to Gaies et al study as follows: VIS= dopamine dose (mcg/kg/min) + dobutamine dose (mcg/kg/min) + 100 x epinephrine dose (mcg/kg/min) +10 x milrinone dose (mcg/kg/min) + 10,000 x vasopressin dose (U/kg/min) + 100 x norepinephrine dose (mcg/kg/min);ICU length of stay;Hospital length of stay ;Incidence of prolonged postoperative mechanical ventilation. | — |
Countries
Egypt
Contacts
Public ContactOssama Mansour
Vice Dean of research committee at faculty of medicine
Outcome results
None listed