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Comparing how safe and effective two herbal products can treat simple malaria with Artemether/Lumefantrine in Ghana

Comparative clinical study of Mist Amen Fevermix and Edhec Malacure: two polyherbal products used for the treatment of uncomplicated malaria in Ghana against Artemether/Lumefantrine

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
PACTR
Registry ID
PACTR202109664146698
Enrollment
150
Registered
2021-09-17
Start date
2019-08-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malaria

Interventions

Amen Fevermix
Edhec Malacure

Sponsors

Bernard K.Turkson
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: • Gender: Male and female • Age: 18 to 45 years • Disease state: Uncomplicated malaria • Absence of severe anaemia • Presence of axillary temperature ~37.5 and < 39.5°C at visit • Informed consent of participants • Patient able and willing to return for follow up.

Exclusion criteria

Exclusion criteria: • Participants with anaemia (haemoglobin <8g/dl) • Patients on treatment with orthodox antimalarial • Any disease condition which might compromise the renal, hepatic or any other body system. • Intake of any medication within 14 days before the start of the study • Presence of clinically significant abnormal laboratory results during screening • Pregnant women • Use of any recreational drugs or a history of drug addiction • Any chronic and communicable disease condition (WHO, 2004).

Design outcomes

Primary

MeasureTime frame
complete treatment of parasitemia and testing for toxicity

Secondary

MeasureTime frame
safety of products

Countries

Ghana

Contacts

Public ContactIsaac K. Amponsah

Senior Lecturer KNUST

akila.amponsah@gmail.com00233243888337

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026