Skin and Connective Tissue Diseases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with non-segmental stable vitiligo(NSV) with two comparable acral lesions, either symmetrical or in the same anatomical area. -patients with non acral vitiligo with lesions at elbows, knees or wrists. -Stability for = 1 year -Age >12years - patients not on treatment for at least 1 month prior to surgery.
Exclusion criteria
Exclusion criteria: Non acral vitiligo in areas other than elbows , knees and wrists . -Segmental vitiligo. - Acral vitiligo responsive to conventional treatment modalities - Active vitiligo; new lesions, expansion of old lesions or koebnerization in < 1 year - Age < 12 years. -pregnant and lactating females.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessing the additive value of PRP to NCES by comparing percent improvement in the lesion via point counting and Vitiligo Extent Score for target lesion VESTA Score . | — |
Secondary
| Measure | Time frame |
|---|---|
| - Assessing the possible influence of disease duration , the age of the patient , the extent of lesional pigmentation prior to therapy (VESTA) and duration of stability on the outcome of the NCES compared to the PRP enriched NCES in patients with stable vitiligo | — |
Countries
Egypt
Contacts
faculty of medicine cairo university