Haematological Disorders Pregnancy and Childbirth Surgery post partum hemorhage
Conditions
Interventions
tranexamic acid prophylaxis to reduce postpartum hemorrhage in vulnerable parturients
intervention without active ingredient or therapeutic effect
Sponsors
University Hospital Lamine Debaghine Bab El Oued
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: - Scheduled or semi-emergency cesarean section. - Live fetus. - Gestational age greater than or equal to 35 SA. - Parturients classified as ASA I or ??,consenting, with 2 or more risk factors for postpartum hemorrhage: * polyhydramnios. * age greater than 35 years. * Fetal macrosomia. * coagulation anomaly. * thrombopenia. * anticoagulant treatment. * antecedents of postpartum hemorrhage. * placenta pravea not recovering. * Anemia. * Pre-eclampsia. * Multiple pregnancy. * Multiple pregnancy. * Chorioamniotitis.
Exclusion criteria
Exclusion criteria: - Allergy to tranexamic acid. - Severe renal impairment. - History of thrombosis. - Epilepsy. - Death in utero - Severe medical or surgical complication involving the heart, liver, kidneys, or brain. - Placental insertion anomalies: placenta accreta and covering pravea. - Caesarean sections performed for active bleeding during uterine rupture, retro placental hematoma, or placenta previa.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| There was statistically significant reduction in the mean blood loss among the study group who received tranexamique acid in comparison to the control group | — |
Secondary
| Measure | Time frame |
|---|---|
| no major side effects | — |
Countries
Algeria
Contacts
Public Contacthouda Ghabouli
resident physician
Outcome results
None listed